The most dangerous diseases in video games

Important points

• Diseases in video games drive the narrative and the player's motivations.

• Some games use disease as a status effect. While some games create terrifying epidemics.

• Different fictional diseases in video games can instill fear and create a unique gaming experience.

Disease is one way that video games can push their narratives forward. Whether it's giving your characters the motivation to continue the plot. or explaining major changes in the world They are a useful tool for any developer.

In some games, disease is just another thing in a long list of status effects that your character can cure, but others like to incite horror and create disasters that will give you nightmares. Of course, it's fictional. But the way the game presents it is realistic enough for you to avoid it at all costs.

Updated November 11, 2024 by Mackenzee Hardyk.: Many games still rely on the fear of getting sick and infected by something you can't cure. It creates an increased sense of awareness and fear for your characters who are inevitably exposed to said bacteria. For this reason, we have decided to update this article with some new items containing the plague and Other forms of epidemics for you to enjoy

13

Guilt

trauma center

Trauma Center: Under the Knife might be famous for making the most of the Nintendo DS stylus. Instead, it is famous for introducing diseases straight out of your childhood nightmares. These diseases, collectively known as GUILT, are part of a complex series of parasites, toxins, and terrorist plots to destroy all of humanity.

Lucky for this world You are a doctor with magical powers derived from the ancient Greek gods of medicine. and repeat an unlimited number of attempts to get the touch controls correct. Its appearance was terrifying. But with a little help from heaven Guilt that the end of the world is just a footnote to humanity's continued rise.

12

Radical-6

The final reward of morality

The Zero Escape series' world-ending bug seems harmless enough compared to most viruses. There is no hemorrhage or coughing at all. Instead, the virus slows down brain function. Makes you perceive time more slowly than it really is.

Although this may not seem like a big deal, But a sudden slowdown will quickly overwhelm your senses. and makes it unbearable to live This means that most people infected with Radical-6 will not die directly from the virus. Instead, they took their own lives. It was dark.

11

gray death

Theus X

You might think that cybernetic enhancements in Deus Ex are a fun way to become good at something without practice. And for the most part, you're right, but while you can use it to make you sneakier than Corvo Attano and outrun Usain Bolt, you're also inviting Gray Death into your body.

Gray Death was first created in a lab to control the population. It infects people through mechanical augmentation. A limited number of vaccines are given only to those who can afford the exorbitant price. Sometimes the price is a lot of money. But sometimes you have to give your allegiance to a secret society that stretches across the globe to stay safe. Perhaps the real plague here is capitalism.

10

Hooligan virus

lost days

The Hooligan virus was created in a lab in Oregon. Unfortunately, there was an intern who was curious. infected with this virus without knowing And within two weeks it had spread all over the world. It also infects animals, making them not only stronger, but also more powerful. But it's also fierce.

Hooligans turn everyone under 12, almost everyone over 60, and anyone with a weakened immune system into freaks or zombies. They will become cannibalistic and violent. And that person's status depends on what they become, such as a child becoming a newt.

9

Biophage

Callisto Protocol

On the moon of Callisto A colony of miners encounters a giant alien. And of course the alien was killed. Scientists have studied it and discovered biological pathogens. Then they started experimenting with it.

Scientists turn people into violent mutants Let them be infected and change despite the consequences. It was the result of Callisto mutating too much. Causing almost everyone on the moon to die. Biophage means devourer of life or devourer of life. Definitely not something you want to deal with.

8

Cordyceps fungus

The last of us

Everyone has their own zombie survival plan these days, but the Cordyceps fungus from The Last of Us threw that all out the window. Sure, you know how to remove the head or destroy the brain. But now you have to avoid the almost invisible fungal spores. And sneak past the mushroom-faced clicker? Hanging out in your local mall doesn't seem so good anymore after you find out that zombies are very fast and can sense movement.

The scariest thing about cordyceps is that it's real. One species of Cordyceps is known to infect the brains of some insects. And although it does not infect humans But it doesn't make the idea any better.

7

Rotten Scarlet

Elden Ring

Technically, of course. You can walk through Scarlet Rot Lake in Elden Ring without much ill effect. But what the putrid rash did to the corners of the Lands Between was nothing short of frightening. Not only was it destroying the land of Caelid, it also seemed to destroy everything it touched. As a result, some victims become unreasonably angry. Even the demigods were not spared.

You can live with decay with magical means like Malenia and Millicent. But getting there was no joy. Especially since it seemed like it would liquify the limbs first. Before going to the core

6

E48K15

One chance

One Chance is a flash game where you only get one chance to play. So you only have one chance to get a favorable outcome. E48K15 comes from a group of scientists working on cancer treatments. This treatment attacks cancer cells.

Unfortunately, the treatment they created doesn't just attack cancer cells after they're released. It floats in the air and begins attacking every living cell. You have only six days to save the world, as the 'cure' is wiping out all life on Earth.

5

Kara

Subnautica

For the most part, you are exploring an alien world filled with water. You weren't too worried about getting sick. You might be more focused on more pressing matters, like not getting eaten by the enormous leviathan-type sea creatures that lurk in the depths.

But disease is exactly what you'll encounter when you dive into the waters of Subnautica. Kharaa is an ancient creature that existed before humanity. It has apparently killed more than 143 billion members of the Precursor race and seems to be at home in every living creature it comes into contact with. Fortunately, there is a cure. But the body count alone should give you a break on your next trip to the beach.

4

Manhattan virus

Crisis 2

The Manhattan Virus is described as a biological weapon created by the Ceph, a group of advanced alien species that seem intent on wiping out humanity. The Ceph releases Manhattan in New York and spreads it through spores. ร

Manhattan virus has many stages. At first it was unclear who was infected. But eventually the virus begins attacking internal organs and quickly causes tumor-like lumps to form. People infected with the virus will die. There is no cure because it develops so rapidly.

3

bite

The story of the epidemic

The Bite is what the people of A Plague Tale call Black Death, if you need a reminder. It's really bad news. More than just showing the devastation of a disease that killed more than a third of Europeans in four years, Asobo Studios has reimagined the pandemic as something far more terrifying. It is spread by hordes of evil rats driven by the forces of darkness.

The Bite may not pack quite as much punch as other games' established maladies. But it's not necessary. The entire continent is still reeling from the trauma of the pandemic. Sometimes just talking about it is enough.

2

Genophage

mass effect

Arguably one of the most brutal tricks in the Council's war arsenal, Mass Effect's Genophage has made it nearly impossible for the Krogan race to reproduce.

Sure, the Krogans wage war nonstop, but the Genophage condemns entire races to death without actually killing them. The scariest thing about the genophage isn't what it does to a single person. it is that it plunges the entire species into an existential crisis.

1

Just all this

Resident Evil

Many ailments in the game turn people into zombies. But few diseases are as evil as the virus the Umbrella Corporation introduced in Resident Evil from day one.

Sure, they'll make you normal zombies, but they'll also turn you into a giant monster with multiple limbs or give you a huge sword. Which would be really cool if it weren't so. Makes it impossible to pick up a glass of water. Many of the viruses in the Resident Evil series have an X factor (or maybe a T factor) that makes their existence truly shocking.